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Yeti Reborn
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After the two Yeti--that Dr. Harry Olson, an American paleoanthropologist, and his wife, Dixie, brought home from the mountains of Mongolia--escaped from the Cinder Mountain Research Facility and were killed by police, one of the scientists in Harry’s anthropology department at California Pacific University, Dr. Millie Harbaum, uses sperm and an egg, taken from the two Yeti before they escaped, to create a baby Yeti and implants the embryo into a female chimp. But unbeknownst to Harry, Millie has added human DNA to the embryo, actually creating a chimera. When the baby, Roku, is born, he is clearly not a full Yeti, and Millie is forced to confess what she has done. Horrified, the university demands that the infant be destroyed immediately. But Millie flees before they can act, taking Roku with her and unleashing a chain of events that may have deadly consequences, not only for Roku and Millie, but for humanity as well...
KUDOS FOR YETI REBORN
In Yeti Reborn by Richard Eddie, Dr. Millie Harbaum, a scientist in Dr. Harry’s Olsen’s anthropology department at Cal Pacific University, takes Yeti DNA and mixes it with human DNA at the Cinder Mountain Research Facility, creating a chimera named Roku. When the university president discovers what she has done, he demands that Millie be fired and Roku destroyed. But before Harry can carry out the president’s orders, Millie flees the facility, taking Roku with her. Now the hunt is on to find Millie and Roku before the public discovers what has happened. Little does Millie know that her actions will have far-reaching effects. The book is both thrilling and educational, giving you a glimpse into the complex world of scientific research while keeping you glued to the edge of your seat. ~ Taylor Jones, The Review Team of Taylor Jones & Regan Murphy
Yeti Reborn by Richard Edde is the story of a scientist with a dream. Millie Harbaum is a scientist in the anthropology department of Cal Pacific University, working at the university’s research facility in Nevada on the top of Cinder Mountain. After the two Yeti that Harry Olson and his wife Dixie brought back from Mongolia escaped and were killed by police, Millie is brokenhearted. The death of the two creatures has put her research, on mapping the genome of the Yeti, on hold. But Millie has frozen sperm and eggs taken from the Yeti before they escaped. She convinces Harry to let her implant an embryo into one of the female chimps at the research facility. But what Millie doesn’t tell Harry is that she has added human DNA to the embryo, and the creature will be a chimera. When the baby is born, Millie’s secret is exposed, and the university is outraged. They order Millie to destroy it, but she refuses. She takes the infant and flees. Now Harry’s job is on the line, as well as the safety of humans if the chimera becomes too much for Millie to handle. Filled with endearing characters, plenty of tension, and fast-paced action, as well as a wealth of fascinating scientific information, Yeti Reborn will catch and hold your interest from beginning to end. ~ Regan Murphy, The Review Team of Taylor Jones & Regan Murphy
Yeti Reborn
Richard Edde
A Black Opal Books Publication
Smashwords Edition
Copyright © 2018 by Richard Edde
Cover Design by Jackson Cover Designs
All cover art copyright © 2018
All Rights Reserved
EBOOK ISBN: 978-1-626949-14-0
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EXCERPT
As much as he hated the idea, Harry knew the creature had to be destroyed, but where was he?
When they returned to the Animal Care Unit, Millie wasn’t there. They found Siscom in the small lab, working.
“How’d it go with Dr. Pauling?” he said after they entered the lab.
Harry ignored the question. “Where’s Millie, Gerald? Have you seen her?” he demanded, his tone terse, his spine stiff.
“Not since you all left here earlier. She may have gone to say goodbye to Roku. She had become very close to that creature. I was going to euthanize it later this afternoon. Funny thing though, I feel I’d be killing Millie in the process. It carries her genome.”
“Millie’s been terminated, Gerald. As of now. I need to tell her. You have no idea where she is?”
“Like I said she might be at Tika’s cage saying goodbye to Roku. Let’s go see. I’d like to be with her when you tell her.”
“Fine,” Harry said, and the trio walked to the cage area.
Millie wasn’t there.
Neither was Roku.
“Okay, Gerald,” Harry said, irritation rising in his voice. “Where is she? She’s gone and taken the chimera with her.”
“I have no idea, Harry, honest.”
Harry strode through the Animal Care Unit, searching the area. “Gerald,” he continued, “it won’t look good on your record if I learn you have abetted her in this travesty and in taking Roku.”
They stopped at the airlock.
“Harry, I swear I knew nothing of Millie’s plan until shortly before delivery, and, by then, it was too late. She never took me into her confidence prior to that. You’ve got to believe me.”
“We do,” Dixie said. “Harry’s just upset. This is a lot to fathom in one afternoon.”
“And deal with,” Harry added.
To my brother, David
“Science is dangerous. There is no question but that poison gas, genetic engineering, and nuclear weapons and power stations are terrifying. It may be that civilization is falling apart and the world we know is coming to an end. In that case, why not turn to religion and look forward to the Day of Judgment...[being] lifted into eternal bliss...[and] watching the scoffers and disbelievers writhe forever in torment.” ~ Isaac Asimov
“Germline therapy...will force us to re-examine even the very notion of what it means to be human [as] we become subject to the same process of conscious design that has so dramatically altered the world around us...Through this technology, we will seize control of our own evolution.” ~ Gregory Stock
“When people began to multiply on the face of the ground, and daughters were born to them, the sons of God saw that they were fair; and they took wives for themselves of all that they chose. Then the Lord said, “My spirit shall not abide in mortals forever, for they are flesh; their days shall be one hundred twenty years.” The Nephilim were on the earth in those days--and also afterward--when the sons of God went in to the daughters of humans, who bore children to them. These were the heroes that were of old, warriors of renown. The Lord saw that the wickedness of humankind was great in the earth, and that every inclination of the thoughts of their hearts was only evil continually. And the Lord was sorry that he had made humankind on the earth, and it grieved him to his heart.” Genesis 6:1-6
Prologue
The clock on the wall read three a.m.
A small LED lamp, directed at the area in front of Dr. Millie Harbaum, was the only illumination for the laboratory workspace. The lab was quiet, only the soft purring of air conditioning broke the silence. Alone in the lab, Millie’s heart raced. Huddled over the desk, she peered at the monitor of the dissecting microscope and adjusted the focus. As the small glistening mass of cells came into sharp relief she caught her breath and thought again of what she was about to do. Was she doing the right thing? she wondered. Or was she about to journey across a line that for years science had been forbidden to broach?
Millie pushed back from the desk, took a deep breath, tried to calm herself, and wiped her moist palms on her lab coat. What she once thought a brilliant idea no
w loomed perilously close to an ethical blunder. But, upon closer reflection, she knew her hand had been forced--forced by a scientific community that did not condone such breakthroughs. Down through history, progress in the sciences had been made by those few men and women who dared to dream the impossible.
Millie dreamed such a dream.
The lab in which she worked was located in the Primate Research Facility on top of a Nevada mountain and was part of the Anthropology Department of California Pacific University. Funded through private donations, the university was located in San Francisco. Millie’s boss, Dr. Miles Radner directed the Primate Research Facility. The facility as a whole and its activities were under the ultimate supervision of the chairman of the department, Dr. Harry Olson. It was Dr. Olson and his team who managed to secure two specimens from Mongolia, the Yeti--a creature once thought only to exist in legends. Dr. Olson and his team of scientists brought the animals to the research facility where, over the following year, they sequenced their entire DNA genome. The work had been difficult and demanding but Millie, who was a graduate research assistant at the time, put her whole life into the project.
Then, there had been a tragic accident. Through a miscalculation of her coworker, both Yeti escaped, killing the coworker in the process. The creatures managed to get off the mountain and terrorized the surrounding countryside, killing a number of people. They were eventually hunted down and destroyed by law enforcement. Everyone, including Dr. Olson, thought it was the end of the Yeti research. Until Millie conceived her experiment.
Now she had her doctorate and was a full-time facility scientist.
And she had a few tricks up her sleeve.
After the deaths of the animals, Dr. Olson gave her the assignment to try and find a way to use the Yeti’s genome. She knew that through the PCR process there was an ample supply of the animal’s DNA. In addition, she and her fellow graduate student collected and stored many Yeti eggs and sperm that were now stored in a freezer down the hallway, waiting to be put to use. Prior to the animal’s escape, Millie injected the female Yeti with HCG, Human Chorionic Gonadotropin, forcing the animal to super-ovulate, and with Dr. Siscom’s help, she collected hundreds of ovum. Sperm was recovered by aspirating the male’s testicle while under sedation. The eggs and sperm now sat frozen, without being utilized for the advancement of science. It was such a waste of good material.
During Millie’s sojourn at the research facility she had became emotionally close to the female Yeti whom she named Sasha. When Sasha and her male counterpart, Bentu, were killed, a part of Millie’s soul died along with the animals. But now, she was on the verge of rekindling that emotional tie. On the cusp of recreating the physical presence of Sasha.
But this time it would be different.
Startlingly different.
The air conditioner whirred, its quiet purring sounding like a sleeping kitten. Millie wiped a strand of hair away from her face, took a deep breath, and said a silent prayer.
She picked up the micropipette that lay on a tray beside the Olympus inverted phase contrast microscope workstation and video monitor. The microscope, suitable for viewing colorless and transparent specimens and live cells, was equipped with a pressure injector connected to a micromanipulator. She stared at it for a moment. Earlier, she had filled the pipette with her own DNA, her exclusive human genome, genetic material that made her unique of all women.
Millie Harbaum’s DNA.
Millie sat back from the video monitor, blinked, then rubbed her face with bare hands. She was tired, nearly exhausted. Glancing around the laboratory, she waited for her eyes to adjust. As they rested, the walls and shelves slowly sharpened in her vision. She took a deep breath then returned to her work. After adjusting again the focusing knob and the diaphragm lever, she squinted at the monitor. Her hand trembled slightly as she fixed the micropipette to the capillary holder and, observing the video monitor, brought it to the edge of the cell membrane. Sasha’s egg cell glimmered in its nutrient solution as she set the injection time and pressure.
Her head swirled with the thought of what she was about to do. She hesitated, momentarily unsure if she wished to proceed, then tried to will her rapid pulse to slow.
Holding her breath, Millie adjusted the scope’s focus one last time then pierced the cell membrane with the micropipette. Using a slow deliberate movement with the micromanipulator, she guided the needle into the cell’s nucleus, pushed the injector and watched the DNA material flow into it. The nucleus bulged briefly then returned to its original shape. After retracting the pipette, Millie took a few moments to observe the cell. Like all cells throughout the animal kingdom it appeared as nothing more than an indistinct sphere under the phase contrast microscope. Satisfied the procedure had gone well, she sat back and took another deep breath.
The clock on the wall read three-twenty a.m.
Millie knew she was embarking on a journey from which there would be no return. Creating another Sasha with her own DNA implanted in its genome was dangerously close to crossing an ethical line never done before. It was one thing to attempt to reproduce a Yeti but to attempt to incorporate her own human DNA into the resulting animal was something never before attempted. It was her hope to create a chimera--DNA from two different species in one organism.
A chimera.
The ethical and moral implications were astronomical.
After receiving her PhD, Millie took Dr. Olson’s offer and became the associate director at the research facility, a position Dr. Radner used to complete all the drudgery work he had no interest in doing. She had a myriad of administrative chores, leaving precious little time to devote to her research. Her genetic engineering project was done solely by her without the help of any other scientists at the facility and certainly without Radner or Dr. Olson’s knowledge. She knew what they would say if they knew. Shut it down. And she couldn’t have that.
Millie had no idea what to expect if her experiment succeeded. She had just fertilized this egg with her own DNA. Now, it was time to incubate the zygote until such time when she would implant it into one of the facility’s chimps. Later, and she had yet to work out all the details, she would force delivery of a newborn Yeti.
Hopefully.
A newborn Yeti that had her genes in its genome.
What would it look like, she wondered? It would be half Yeti, half human. Was she unleashing a scientific monster in the legacy of golden age horror movies?
She took the Petri dish from the dissecting scope, covered it, and placed it in the thermal convection incubator. Returning to her chair at the workstation, she turned off the light and sat in the dark contemplating what she had done. It was not too late. She could destroy the cell. She knew at some point she would have to tell Dr. Radner and Dr. Olson of her experiment but she decided to wait until she was forced to do so. Once the embryo was successfully implanted into a chimp.
She was aware that several bioethicists called for a ban on species-altering technologies that would be enforced by an international tribunal. Part of the rationale for this ban was the concern that such technologies could be used to create a slave race, that is, a race of sub-humans that could be exploited. Earlier in the decade, two scientists who were both opposed to genetically modified organisms applied for a patent for a humanzee--part human and part chimpanzee--to intentionally fuel debate on the issues and draw attention to potential abuses. The United States Patent and Trademark Office denied the patent on the grounds that it violated the Thirteenth Amendment of the Constitution of the United States, which explicitly prohibited slavery.
The prospect of bioengineered life forms raised important questions about how a person was defined in both legal and ethical terms.
Although the USPTO permitted the extensive patenting of bioengineered life forms, the question raised by the scientists’ application was one that could easily be resolved by answering a simple question. What constitutes a person? A genetic definition was not very helpful, given the varia
bility of gene sequences between individuals. And a species definition could be controversial. When experts looked to specific characteristics for a definition, they were faced with the fact that humans shared many characteristics with primates and other animals, so where could they draw the line?
If science created a being that had the ability to speak and perhaps even reason, but looked like a dog or a chimp, should that creation be given all the rights and protection traditionally bestowed upon a person? Some bioethicists argued that the definition of human being should be more expansive and protective, rather than more restrictive. Others argued that more expansive definitions could minimize humanity’s status and create a financial disincentive to patenting creations that could be of potential use.
The question of whether the definition should be more expansive or restrictive would ultimately be considered as courts, legislatures, and institutions address laws regarding genetic discrimination.
Opponents of genetic manipulation feared the prospect of creating a race of super-humans, while proponents supported the right to give children every advantage.
In a similar vein, the medical director of the International Olympic Committee expressed concern that athletes employ genetic engineering to get an edge over their competition. If individuals were willing to genetically manipulate their children to make them better athletes, then it was likely that individuals would be willing to manipulate their children to better looking, more musically inclined, or whatever else might give them an advantage. Opponents of genetic manipulation argue that, by allowing this, we run the risk of creating a race of superhumans, changing what it means to be normal and increasing the ever-widening gap between the haves and the have-nots. Proponents argue that currently parents can and do give their children advantages by sending them to better schools or giving them growth hormones, and that banning genetic manipulation is a denial of individual liberties. Finally, Millie realized, these arguments reflected the opposing philosophies regarding how scarce resources would and should be allocated in the future.